An experimental study of reparative osteogenesis with titanium implants use

During the experiment the implantation of titanium implants (prototypes) obtained by the technology of selective laser sintering (SLS) using a 3D printer was made. Implants were placed into the rabbits’ mandible bodies. In order to study the processes of reparative osteogenesis, microsamples of periimplantation zone tissues were analyzed. As a result, signs of osteo- and fibro-osseointegration were identified, which can be regarded as a prerequisite for further clinical trials with titanium of this brand.

Keywords: reparative osteogenesis, titanium implant (prototype)

The authors declare no conflict of interest. Source of financing.

The work was financially supported by the Ministry of Education and Science of the Russian Federation, a subsidy for the implementation of complex projects for the creation of high-tech production as part of the implementation of the Government Decree from April 9, 2010 No. 218, line 8 on the topic “Creating high-tech digital production of precision metal complexes for implantation based on additive technologies ”, agreement number 03.G25.31.0234 of 03.03.2017.

For citation: Reshetov I.V., Svyatoslavov D.S., Samoilova S.I., Dolgolev A.A., Gareev A.F., Ruban K.M. An experimental study of reparative osteogenesis with titanium implants use. Голова и шея  Head and neck Russian Journal. 2018; 6(2):6–11 (in Russian).

The authors are responsible for the originality of the data presented and the possibility of publishing illustrative material – tables, figures, photographs of patients.