For citation: Kirasirova E.A., Frolkina E.A., Rezakov R.A., Mamedov R.F., Lafutkina N.V., Rybalchenko I.E., Tyutina S.I., Trusov V.A. Use of thermal helium-oxygen mixture for correction of respiratory failure in complex treatment of patients with cicatricial stenosis of larynx and trachea. Head and neck. Russian Journal. 2022;10(4):24–29
The relevance of the work is determined by the fact that the result of treatment of patients with chronic larynx and trachea stenosis depends not only on the method of treatment, but also on the effect on postoperative tissue repair in conditions of chronic respiratory failure, which accompanies cicatricial stenosis of the larynx and trachea (CSLT). Development of new noninvasive techniques eliminating the consequences of hypoxia is a promising direction of respiratory support in the complex treatment of patients with chronic laryngeal and tracheal stenosis.
The article analyzes the effectiveness of correction of respiratory disorders using a thermal helium-oxygen mixture (Heliox) in patients with chronic cicatricial stenosis of the larynx and trachea. The study included 41 patients aged 19-67 years with a disease duration of 2 months to 16 years.
The necessary clinical and radiation, endoscopic and functional examination was performed on an outpatient basis. To detect chronic respiratory failure, the gas and acid-base composition of arterial blood was assessed. In the hospital, all patients underwent surgical intervention in the required volume. All patients in the pre- and postoperative period received inhalation therapy with a thermal helium-oxygen mixture according to the developed algorithm. After discharge from the hospital, a dynamic outpatient observation was carried out for 6 months.
The study showed that an integrated approach to the treatment using a thermal helium-oxygen mixture (Heliox) to correct respiratory disorders and manifestations of chronic hypoxia is a promising method for pre- and postoperative management of patients with cicatricial stenosis of the larynx and trachea.
Key words: cicatricial stenosis of the larynx and trachea, chronic respiratory failure, hypoxia, helium-oxygen mixture, Heliox
Conflicts of interest. The authors have no conflicts of interest to declare.
Funding. There was no funding for this study