Volodina V.D., Reshetov I.V., Serova N.S., Romanko Yu.S. The Utility of Radiation Imaging during the Treatment of Head and Neck Tumors with Neoadjuvant Chemotherapy. Head and neck. Russian Journal. 2023;11(2):75–80 The authors are responsible for the originality of the data presented and the possibility of publishing illustrative material – tables, drawings, photographs of patients.
Head and neck cancer ranks 6th–7th in incidence among all cancers worldwide. In 90-95% of cases, head and neck cancer is presented by squamous cell carcinoma of various degrees of differentiation. The mean age at the time of diagnosis is approximately 60 years. Nowadays, chemotherapy plays a key role in the treatment of malignant tumors of oral cavity and pharynx and can be used both as part of chemoradiotherapy (neoadjuvant chemotherapy followed by radiotherapy or concomitant chemoradiotherapy) and as an independent treatment option for recurrent, unresectable disease and regional metastasis. Neoadjuvant chemotherapy is a form of medical treatment applied before surgery or radiotherapy and is one of the most promising treatment options for oral and oropharyngeal cancer. Currently, the criteria for neoadjuvant chemotherapy response assessment with radiation imaging are not well-defined. The article analyzes the current data on the use of radiation diagnostic methods in assessing the effectiveness of neoadjuvant chemotherapy.
Key words: head and neck tumors, squamous cell carcinoma, neoadjuvant chemotherapy, radiation diagnostics, computed tomography, magnetic resonance imaging, ultrasound, diagnostics
Conflicts of interest. The authors have no conflicts of interest to declare.
Funding. There was no funding for this study