Nazarov V.V., Chukumov R.M., Ilyin M.V., Ostaev Ju.A., Okshin D.Ju., Ektova A.P., Rogozhin D.V., Linde N.N., Batalov A.I., Tlisova M.N., Spirin D.S., Cherekaev V.A., Matuev K.B., Svyatoslavov D.S., Reshetov I.V. Navigation-assisted surgery for pyrophosphate arthropathy of the temporomandibular joint. Head and neck. Russian Journal. 2023;11(1):44–53
The authors are responsible for the originality of the data presented and the possibility of publishing illustrative material – tables, drawings, photographs of patients.


Background. Pyrophosphate arthropathy (calcium pyrophosphate dihydrate deposition disease) refers to rare deposition disorders with the onset of the disease after 55 years, manifested by the formation and deposition of calcium pyrophosphate crystals in the joint area, which leads to aseptic inflammation of an immune nature. Clinical manifestations of calcium pyrophosphate accumulation disease are similar to those of various degenerative and inflammatory joint lesions, as well as tumors. With the progression of pyrophosphate arthropathy, surgical treatment is required, which includes both histological verification and complex reconstructive interventions involving a neurosurgeon and a maxillofacial surgeon.

Case description. We present a clinical case of pyrophosphate arthropathy of temporomandibular joint with a spread to the middle cranial fossa and propose an algorithm for the treatment of such lesions.

Conclusion. Modern computer modeling technologies and experience in the use of various materials for allotransplantation make it possible to perform one-stage surgical treatment with resection and reconstruction of the temporomandibular joint. However, further studies are needed to assess the long-term results of the use of personalized implants in order to assess tissue reactions, the frequency of infectious complications, and prosthesis migration.

Key words: skull base tumors, navigation, neurosurgery, maxillofacial surgery, temporomandibular joint, deposition diseases, pyrophosphate arthropathy, pyrophosphate
Conflicts of interest. The authors have no conflicts of interest to declare.
Funding. There was no funding for this study

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