Reshetov I.V., Sukortseva N.S., Shevalgin A.A., Agakina Yu.S., Bagdasarov P.S., Nasilevsky P.A. Combined method of oropharyngeal cancer treatment: a clinical case. Head and neck Russian Journal. 2018;6(4):37–43 (in Russian).
Background. Determining the treatment tactics for patients with oropharyngeal cancer is always a challenging problem. The treatment method choice is usually based on the clinical manifestation of the disease and its stage.
For resectable oropharyngeal tumors (squamous cell carcinoma, adenocarcinoma), various treatment methods are used, one of which is three-component induction chemotherapy (TPF regimen, 2-3 cycles) with clinical effect assessment and further surgical treatment. In case of early cancer, transoral robot-assisted surgery is possible, which opens up a new era in oropharyngeal malignancies surgery being minimally invasive, precise and easy. One more equally important factor is the possibility to restore the function of the operated organ, coupled with affecting the patient’s quality of life.
Purpose: the introduction of neoadjuvant chemotherapy (TPF regimen) in combination with transoral robotic surgery (TORS) into clinical practice of early (T1-2) oropharyngeal cancer patients’ treatment.
Material and methods. An induction chemotherapy (TPF regimen, 2–3 courses with docetaxel 75 mg/m2 , cisplatin 75 mg/m2 , 5-fluorouracil 1000 mg/m2 ) followed by transoral robot-assisted resection of the oropharynx was used for the treatment of a patient with oropharyngeal squamous cell carcinoma and presented as a clinical case. Conclusion: such treatment tactics allows proceeding to the next stages of therapy (chemotherapy, radiation therapy) in the short period, providing complex treatment of patients with oropharyngeal and oral cavity tumors.
Key words: oropharyngeal cancer, transoral robotic surgery, induction chemotherapy, TORS
The authors declare no conflict of interest.
Source of financing: not specified.
For citation: Reshetov I.V., Sukortseva N.S., Shevalgin A.A., Agakina Yu.S., Bagdasarov P.S., Nasilevsky P.A. Combined method of oropharyngeal cancer treatment: a clinical case. Head and neck Russian Journal. 2018;6(4):37–43 (in Russian).
The authors are responsible for the originality of the data presented and the possibility of publishing illustrative material – tables, figures, photographs of patients.