Egorov V.I., Magomedov M.U., Mustafaev D.M. Effectiveness of NO-therapy in the complex treatment of rhinophyma. Results of a clinical trial. Head and neck. Russian Journal. 2021;9(4):8–13 (In Russian).
The authors are responsible for the originality of the data presented and the possibility of publishing illustrative material – tables, figures, photographs of patients.

Rhinophyma is a rather common disease resulting in considerable enlargement and hypertrophy of the nasal skin elements along with persistent cosmetic defect in the patient’s appearance. The results of the clinical trial aimed to increase the efficiency of complex treatment of patients with rhinophyma are presented in the article.
Purpose of the study. To improve the effectiveness of treatment of rhinophyma using NO-therapy in the postoperative period.

Material and methods. Patients diagnosed with rhinophyma were included in the study. The median age of the patients was 64.5 years. The participants from both groups underwent surgery to remove rhinophyma using cold plasma. In the main group (n=25), maximum mode NO-therapy was used in the first 7 days after the surgical treatment of rhinophyma, whereas the control group (n=25) patients did not undergo NO-therapy The degree of microcirculation was assessed by laser Doppler flowmetry (LDF). The condition of the emerging postoperative scar was assessed using the OSAS and PSAS scales, and the severity of the rhinophyma was assessed using the RHISI index.
Results and discussion: The study results support the effectiveness of NO-therapy in the complex treatment of rhinophyma. The authors discuss the necessity of rhinophyma treatment using NO-therapy to increase the efficiency of epidermis restoration, obtaining more favorable cosmetic effect and, as a consequence, decreasing the number of bed-days of inpatient stay.

Key words: rhinophyma, treatment, cold plasma, NO-therapy, microcirculation, regeneration.

Conflicts of interest.
The authors have no conflicts of interest to declare.
There was no funding for this study.
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