Combined treatment of recurrent laryngeal papillomatosis in adults using a CO2 laser and photodynamic therapy – I.I. Nazhmudinov, I.G. Guseynov

The aim of the study was to evaluate the results of a combined treatment for recurrent laryngeal papillomatosis in adults using two stages: initial removal of papillomas with a CO2-laser followed by photodynamic therapy. Material and мethods. Between 2019 and 2021, 75 adult patients with recurrent laryngeal papillomato-sis were treated using this new treatment approach. The treatment outcome was assessed using a scale for evaluating the severity of recurrent laryngeal papilloma proposed by the authors. Results. 72 (96%) patients showed a decrease in the prevalence score, indicating a reduction in the total number of papillomas. 3 (4%) patients had no change in the prevalence of papillomas in their larynx. Conclusion. The use of a combined treatment method for recurrent laryngeal papillomatosis is an effective and promising approach, with the potential to significantly improve patient quality of life and reduce the severity of laryngeal lesions. Keywords: laryngeal papillomatosis, photodynamic therapy, evaluation of laryngeal papilloma preva-lence Conflicts of interest. The authors have no conflicts of interest to declare. Funding. There was no funding for this study