Radiation therapy and its objectives within the framework of the First International Interdisciplinary Congress on Nuclear Medicine and Oncology “University Clinics” of the Federal State Budgetary Institution Russian Scientific Center of Roentgen Radiology (RSCRR) of the Ministry of Healthcare of the Russian Federation (Russian Scientific Center of Roentgen Radiology)

Despite advances in ideological and scientific-technical technologies in oncology, a serious problem has persisted since 2020: according to GLOBOCAN, there were 19,292,789 newly diagnosed patients with malignant tumors and 9,058,133 cancer deaths worldwide. In recent years, research aimed at developing specific markers – “radioactive agents” – has intensified. An important development has been the discovery of fibroblast activation protein (FAP), a transmembrane glycoprotein expressed on activated fibroblasts, including cancer-associated fibroblasts (CAFs). A new direction is related to the study of radio-labeled fibroblast activation inhibitors, FAPIs, as markers for PET/CT in cancer diagnosis and tumor border determination for use in planning and contouring targets for radiation exposure. However, no scientific issue can be resolved without the involvement of multidisciplinary pedagogical and technical support within various scientific schools. A deep connection between the production of medical equipment and clinical oncology is needed, and Rosatom and Rostec State Corporations have successfully coped with these tasks. Routine healthcare is supported by the development and implementation of domestic automated systems for 3–4-dimensional contouring of tumors and volumetric organs at risk based on mathematical programs that consider the algorithms of clinical, physical, and radiobiological data on an individual patient. It is necessary to accelerate the development and implementation of domestic imaging systems based on mobile cone-beam computed tomography (CBCT). It is also necessary to improve radiation therapy techniques in the context of radiation exposure in patients with transplants, such as breast implants. Partially lost technologies of interstitial radiation therapy for localized breast cancer have previously demonstrated their indisputable effectiveness in the Federal State Budgetary Institution Russian Scientific Center of Roentgen Radiology (RSCRR) of the Ministry of Healthcare of the Russian Federation (Russian Scientific Center of Roentgen Radiology) and can be replicated in a cost-effective manner in new conditions today.
Keywords: radiation therapy, malignant tumors
Conflict of interest. The author has no conflicts of interest.
Funding. Absent.