Implementation of the principles of oncological alertness in the treatment of patients with pathological processes of the oral mucosa

Background. Due to frequent traumatization, especially in the presence of harmful habits, the oral mucosa is
subject to high risks of cancer development during a person’s life. Early diagnostics of possible mucosal cancers
during dental examination is a basic principle of cancer awareness. However, despite this, the disease is frequently
diagnosed only at stages III-IV, when the main therapeutic measures are symptomatic and palliative.
Clinical Cases are presented from the practice of early detection of carcinoma in situ in patient Y., 48 years old
and patient B., 35 years old, who consulted a dental clinic for clinical professional cleaning of teeth.
Conclusion. If a malignant process of the oral mucosa is suspected at the stage of the dental polyclinic, the use of enzyme-linked immunosorbent assay of the oral fluid allows to increase the diagnostic performance non-invasively.
The inclusion of saliva enzyme-linked immunosorbent assay in the algorithm improves the diagnostic efficacy and allows early detection of oral squamous cell carcinoma.
Key words: oral fluid, dental status, matrixins, early diagnosis, cancer, oral mucosa
Conflicts of interest. The authors have no conflicts of interest to declare.
Funding. There was no funding for this study.